I make my most my money from removing spyware. Spybot is ok but misses soo much stuff, it detects it all but has major issues removing it. Malware bytes is a lot more effective, there is a free version for none business use.
I am finding these days it is quicker to do a full backup and reformat the computer depending on the setup. I used to do this as a last resort but on basic systems it is usually a lot quicker just to format the damn thing.
The problem with Spybot is it may remove it for a day or too but the next day the DLL attached to explorer.exe will make new registery enteries so it will just come back again.
Spybot is good for detecing spyware but not good at removing it.